Lin, Keng-hui / Research Fellow

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Contact Information

Education

  • 2009 Physiology Course, Marine Biological Laboratory, Woods Hole, MA, USA
  • PhD, Dept. of Physics and Astronomy, University of Pennsylvania
  • B.S., Dept. of Physics, National Taiwan University

Secretary

Chen, Vicky / 886-2-2789-8948

wcchen [at] phys.sinica.edu.tw

Research Interest

  • Experimental Soft Condensed Matter Physics
  • Microfluidics
  • Nano- and micro- material Assembly
  • Biophysics
  • Tissue Engineering
  • 3D Cell Culture
  • Mechanics of Solid Foam

獎項及殊榮

(1) 國內學術研究獎項 2016-12 國家新創獎-最佳產業效益獎
(2) 國內學術研究獎項 2013-03 台灣女科學家新秀獎 (Taiwan Outstanding Young Female Scientist Award)
(3) 其他國際學術研究獎項 2011-08 TWAS Young Affiliates

Experience

  • Postdoc, Dept. of Chemistry and Chemical Biology, Harvard University
  • Visiting Scholar, Harvard University
  • Assistant Research Fellow, Academia Sinica (2004-2011)
  • Associate Research Fellow, Institute of Physics, Academia Sinica (2011-Current)
  • Adjunct Associate Professor, National Central University (2005-2011)

Research Achievements

Journal Papers

  • [1]     De Leon Marco P., Wen Fu-Lai, Paylaga Giovanni J., Wang Ying-Ting, Roan Hsiao-Yuh, Wang Chung-Han, Hsiao Chung-Der, Lin Keng-Hui, Chen Chen-Hui, 2023, “Mechanical waves identify the amputation position during wound healing in the amputated zebrafish tailfin”, Nature Physics, 19, 1362-1370. (SCIE) (IF: 19.684; SCI ranking: 4.7%)

  • [2]     Ambattu LA, Knight C, Lin KH, Gelmi A, Yeo LY, 2023, “Calcium-dependent cAMP mediates the mechanoresponsive behaviour of endothelial cells to high-frequency nanomechanostimulation.”, Biomaterials, 292, 121866. (SCIE) (IF: 15.304; SCI ranking: 4.1%,6.5%)

  • [3]     Wu MC, Yu HW, Chen YQ, Ou MH, Serrano R, Huang GL, Wang YK, Lin KH, Fan YJ, Wu CC, Del Alamo JC, Chiou A, Chien S, Kuo JC, 2023, “Early committed polarization of intracellular tension in response to cell shape determines the osteogenic differentiation of mesenchymal stromal cells.”, Acta biomaterialia, 163, 287-301. (SCIE) (IF: 10.633; SCI ranking: 13.3%,15.2%)

  • [4]     Saw Thuan Beng, Gao Xumei, Li Muchun, He Jianan, Le Anh Phuong, Marsh Supatra, Lin Keng-hui, Ludwig Alexander, Prost Jacques, Lim Chwee Teck, 2022, “Transepithelial potential difference governs epithelial homeostasis by electromechanics”, Nature Physics, 18(9), 1122-1128. (SCIE) (IF: 19.684; SCI ranking: 4.7%)

  • [5]     Kao TW, Chiou A, Lin KH, Liu YS, Lee OK, 2021, “Alteration of 3D Matrix Stiffness Regulates Viscoelasticity of Human Mesenchymal Stem Cells.”, International journal of molecular sciences, 22(5), 2441. (SCIE) (IF: 6.208; SCI ranking: 23.2%,27.8%)

  • [6]     Lin Jong-Wei, Huang Yi-Man, Chen Yin-Quan, Chuang Ting-Yun, Lan Tien-Yun, Liu Yen-Wenn, Pan Hung-Wei, You Li-Ru, Wang Yang-Kao, Lin Keng-hui, Chiou Arthur, Kuo Jean-Cheng, 2021, “Dexamethasone accelerates muscle regeneration by modulating kinesin-1-mediated focal adhesion signals”, Cell Death Discovery, 7(1), 35. (SCIE) (IF: 7.113; SCI ranking: 29.2%)

  • [7]     Huang CK, Paylaga GJ, Bupphathong S, Lin KH, 2020, “Spherical microwell arrays for studying single cells and microtissues in 3D confinement.”, Biofabrication, 12(2), 025016. (SCIE) (IF: 11.061; SCI ranking: 9.2%,10.9%)

  • [8]     Cheng-Nan Yang, Li-Syuan Liang, Keng-hui Lin, Wen-Yea Jang, 2019, “The mechanical properties of monodisperse foam scaffolds”, Composites Part B: Engineering, 164, 517-523.

  • [9]     Lin Han-Yuan, Chu Li-An, Yang Hsuan, Hsu Kuo-Jen, Lin Yen-Yin, Lin Keng-Hui*, Chu Shi-Wei*, Chiang Ann-Shyn*, 2019, “Imaging through the Whole Brain of Drosophila at λ/20 Super-resolution”, iScience, 14, 164-170. (SCIE) (IF: 6.107; SCI ranking: 20.3%)

  • [10]     Doss BL, Rahmani Eliato K, Lin KH, Ros R, 2019, “Quantitative mechanical analysis of indentations on layered, soft elastic materials”, Soft matter, 15(8), 1776-1784. (SCIE) (IF: 4.046; SCI ranking: 48.5%,43.9%,29.1%,27.8%)

  • [11]     Guo-wei Jheng, Sung Sik Hur, Chia-ming Chang, Jia-Shing Cheng, Hsiao-hui Lee, Bon-chu Chung, Yang-kao Wang, Keng-hui Lin, Juan C. del Alamo, Shu Chien, Jin-wu Tsai*, 2018, “Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration.”, Biochemical and biophysical research communications, 497(3), 869-875. (SCIE) (IF: 3.322; SCI ranking: 66%,54.2%)

  • [12]     Han J, Lin KH, Chew LY, 2017, “Study on the regulation of focal adesions and cortical actin by matrix nanotopography in 3D environment.”, Journal of physics. Condensed matter : an Institute of Physics journal, 29(45), 455101.

  • [13]     Chen-chie Wang, Kai-chiang Yang, Keng-hui Lin, Yen-liang Liu, Ya-Ting Yang, Tzong-Fu Kuo, Ing-Ho Chen, 2016, “Expandable Scaffold Improves Integration of Tissue-Engineered Cartilage: An In Vivo Study in a Rabbit Model.”, TISSUE ENGINEERING, 22(11-12), 873-84.

  • [14]     Chen-en Wu, Keng-hui Lin, Jia-yang Juang, 2016, “Hertzian load-displacement relation holds for spherical indentation on soft elastic solids undergoing large deformations”, TRIBOLOGY INTERNATIONAL, 97, 71-76. (SCIE) (IF: 5.62; SCI ranking: 10.9%)

  • [15]     Yin-Ping Lo, Yi-Shiuan Liu, Marilyn G. Rimando, Jennifer Hui-Chun Ho, Keng-hui Lin and Oscar K. Lee*, 2016, “Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells”, SCIENTIFIC REPORTS, 6, 21253. (SCIE) (IF: 4.997; SCI ranking: 25.7%)

  • [16]     Wen-Ting Hsieh, Yi-Shuan Liu, Yi-hsuan Lee, Rimando, Marilyn Rimando, Keng-hui Lin*, Oscar K. Lee*, 2016, “Matrix dimensionality and stiffness cooperatively regulate osteogenesis of mesenchymal stromal cells”, ACTA BIOMATERIALIA, 32, 210. (SCIE) (IF: 10.633; SCI ranking: 13.3%,15.2%)

  • [17]     Bishnubrata Patra, Yu-Sheng Peng, Chien-Chung Peng, Wei-Hao Liao, Yu-An Chen, Keng-Hui Lin, Yi-Chung Tung, Chau-Hwang Lee, 2014, “Migration and vascular lumen formation of endothelial cells in cancer cell spheroids of various sizes”, Biomicrofluidics, 8(5), 052109. (SCIE) (IF: 3.258; SCI ranking: 50.6%,55.6%,69.1%,35.3%)

  • [18]     Chen-chie Wang, Kai-Chiang Yang, Keng-hui Lin, Chang-chin Wu, Yen-liang Liu, Feng-Huei Lin, Ing-ho. Chen, 2014, “A biomimetic honeycomb-like scaffold prepared by flow-focusing technology for cartilage regeneration.”, Biotechnology and bioengineering, 111(11), 2338-48. (SCIE) (IF: 4.395; SCI ranking: 34.8%)

  • [19]     Thai-Yen Ling, Yen-Liang Liu, Yung-Kang Huang, Sing-Yi Gu, Hung-Kuan Chen, Choa-Chi Ho, Po-Nien Tsao, Yi-Chung Tung, Huei-Wen Chen, Chiung-Hsiang Cheng, Keng-Hui Lin, Feng-Huei Lin, 2014, “Differentiation of lung stem/progenitor cells into alveolar pneumocytes and induction of angiogenesis within a 3D gelatin--microbubble scaffold.”, Biomaterials, 35(22), 5660-9. (SCIE) (IF: 15.304; SCI ranking: 4.1%,6.5%)

  • [20]     Yi-hsuan Lee, Jung-ren Huang, Yang-kao Wang, and Keng-hui Lin*, 2013, “Three-dimensional fibroblast morphology on compliant substrates of controlled negative curvature ”, Integrative Biology, 5(12), 1447. (SCIE) (IF: 3.177; SCI ranking: 75.9%)

  • [21]     Yung-Shin Sun, Shih-Wei Peng, Keng-Hui Lin, and Ji-Yen Cheng, 2012, “Electrotaxis of lung cancer cells in ordered three-dimensional scaffolds”, Biomicrofluidics, 6(1), 14102. (SCIE) (IF: 3.258; SCI ranking: 50.6%,55.6%,69.1%,35.3%)

  • [22]     Chen-Chie Wang, Kai-Chiang Yang, Keng-Hui Lin, Yen-Liang Liu, Hwa-Chang Liu, Feng-Huei Lin, 2012, “Cartilage regeneration in SCID mice using a highly organized three-dimensional alginate scaffold.”, Biomaterials, 33(1), 120-7. (SCIE) (IF: 15.304; SCI ranking: 4.1%,6.5%)

  • [23]     Chen-chie Wang, Kai-chiang Yang, Keng-hui Lin, Hwa-Chang Liu, Feng-huei Lin*, 2011, “A highly organized three-dimensional alginate scaffold for cartilage tissue engineering prepared by microfluidic technology.”, Biomaterials, 32(29), 7118-26. (SCIE) (IF: 15.304; SCI ranking: 4.1%,6.5%)

  • [24]     Jing-ying Lin, Wan-jung Lin, Wei-hong Hong, Hsiang-haw Ning, Wei-chun Hung, Stephanie H. Nowotarski, Susana Montenegro Gouveia, Ines Cristo, and Keng-hui Lin*, 2011, “Morphology and organization of tissue cells in 3D microenvironment of monodisperse foam scaffolds”, SOFT MATTER, 7, 10010. (SCIE) (IF: 4.046; SCI ranking: 48.5%,43.9%,29.1%,27.8%)

  • [25]     Chi-Chih Ho, Po-Yuan Chen, Keng-Hui Lin, Wen-Tau Juan, Wei-Li Lee, 2011, “Fabrication of Monolayer of Polymer/Nanospheres Hybrid at a Water-Air Interface.”, ACS applied materials & interfaces, 3(2), 204. (SCIE) (IF: 10.383; SCI ranking: 14.2%,20.9%)

  • [26]     Chi-chih Ho, Tung-wu Hsieh, Hsiang-Hsi Kung, Wen-Tau Juan, Keng-Hui Lin, and Wei-Li Lee, 2010, “Reduced Saturation Magnetization in Cobalt Antidot Thin Films Prepared by polyethylene oxide-assisted self-assembly of polystyrene nanospheres”, Applied Physics Letter, 96, 122504.

  • [27]     Kuo-yuan Chung, Narayan Chandra Mishra, Chen-chi Wang, Feng-hui Lin, and Keng-hui Lin*, 2009, “Fabricating Scaffolds by Microfluidics”, Biomicrofluidics, 3(2), 022403. (SCIE) (IF: 3.258; SCI ranking: 50.6%,55.6%,69.1%,35.3%)

  • [28]     Po-Keng Lin, Keng-hui Lin, Chi-Cheng Fu, K.-C. Lee, Pei-Kuen Wei, Woei-Wu Pai, Pei-Hsi Tsao, Y.-L. Chen and W. S. Fann, 2009, “One-Dimensional Dynamics and Transport of DNA Molecules in a Quasi-Two-Dimensional Nanoslit”, Macromolecules, 42,1770-1774. (SCIE) (IF: 6.057; SCI ranking: 11.1%)

  • [29]     Keng-hui Lin*, Liang-jie Lai, Chih-chung Chang, and Hui Chen, 2008, “Assembly of Microspheres with Polymers by Evaporating Emulsion Droplets”, PHYSICAL REVIEW E, 78, 041408. (SCIE) (IF: 2.707; SCI ranking: 47.1%,17.9%)

  • [30]     Wang WU, Chen C,Lin KH, Fang Y, Lieber CM, 2005, “Label-free detection of small-molecule-protein interactions by using nanowire nanosensors.”, Proceedings of the National Academy of Sciences of the United States of America, 102(9), 3208-12. (SCIE) (IF: 12.779; SCI ranking: 12.2%)

  • [31]     Islam MF, Lin KH, Lacoste D, Lubensky TC, Yodh AG, 2003, “Field-induced structures in miscible ferrofluid suspensions with and without latex spheres.”, Physical review. E, Statistical, nonlinear, and soft matter physics, 67(2 Pt 1), 021402.

  • [32]     M.C. McAlpine, R.S. Friedman, S. Jin, K.H. Lin, W.U. Wang, C.M. Lieber, 2003, “High-performance nanowire electronics and photonics on glass and plastic substrates”, NANO LETTERS, 3(11), 1531-1535. (SCIE) (IF: 12.262; SCI ranking: 11.1%,15.2%,9.2%,15.5%,8.1%,14.5%)

  • [33]     Mach P, Wiltzius P, Megens M, Weitz DA, Lin Kh KH, Lubensky TC, Yodh AG, 2002, “Electro-optic response and switchable Bragg diffraction for liquid crystals in colloid-templated materials.”, Physical review. E, Statistical, nonlinear, and soft matter physics, 65(3 Pt 1), 031720.

  • [34]     Peter Mach, P. Wiltzius, M. Megens, D. A. Weitz, Keng-hui Lin, T. C. Lubensky, Arjun G. Yodh, 2002, “Electro-optic response and switchable Bragg diffraction for liquid crystals in colloid-templated materials.”, PHYSICAL REVIEW E, 58, 679. (SCIE) (IF: 2.707; SCI ranking: 47.1%,17.9%)

  • [35]     Lau AW, Lin KH, Yodh AG*, 2002, “Entropic interactions in suspensions of semiflexible rods: short-range effects of flexibility.”, Physical review. E, Statistical, nonlinear, and soft matter physics, 66(2 Pt 1), 020401.

  • [36]     J. Zhang, A. Alsayed, Keng-hui Lin, S. Sanyal, F. Zhang, W-J. Pao, V. S. K. Balagurusamy, P. A. Heiney, and A. G. Yodh, 2002, “Template-Directed Convective Assembly of 3D Face-Centered-Cubic Colloidal Crystals ”, APPLIED PHYSICS LETTERS, 81, 3176. (SCIE) (IF: 3.971; SCI ranking: 31.1%)

  • [37]     Keng-hui Lin, John C. Crocker, Ana C. Zeri, Arjun G. Yodh*, 2001, “Colloidal interactions in suspensions of rods.”, PHYSICAL REVIEW LETTERS, 87(8), 088301. (SCIE) (IF: 9.185; SCI ranking: 9.3%)

  • [38]     A.G. Yodh, Keng-hui Lin, J. C. Crocker, A. D. Dinsmore, R. Verma, and P. D. Kaplan, 2001, “Entropically Driven Self-Assembly and Interaction in Suspension”, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 359, 921. (SCIE) (IF: 4.019; SCI ranking: 32.4%)

  • [39]     Keng-hui Lin, John C. Crocker, Vikram V. Prasad, Andrew Schofield, David A. Weitz, T. C. Lubensky, Arjun G. Yodh*, 2000, “Entropically driven colloidal crystallization on patterned surfaces”, PHYSICAL REVIEW LETTERS, 85(8), 1770-1773. (SCIE) (IF: 9.185; SCI ranking: 9.3%)

Others

  • [1]     林耿慧，2005，〈膠體粒子的布朗運動〉，《物理雙月刊》，第 27 卷 3 期 470-474。

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