Guo,Chin-Lin / Associate Research Fellow


Contact Information



Rao, Cindy / 886-2-2789-8916

Research Interest

  • cellular mechanisms of self-organization in biological systems, the biomechanics that enhance and stabilize spatiotemporal control


  • 2001. Assistant Professor, 2006-14; Caltech, 2014


Journal Papers

  • [1]     Tsai, Y. L. Yeh, P. Y. Huang, C. J. Guo, C. L. Chang, Y. C., 2019, “Scalable Multilayer Cell Collector to Capture Circulating Tumor Cells with an Unlimited Volume Capacity”, ACS BIOMATERIALS SCIENCE & ENGINEERING, 5(6), 2725-2731. (SCI, SSCI) (IF: 4.432; SSCI ranking: 30.8%)

  • [2]     J-Y. Yu, S. Kim, D. B. Holland, M. A. Allodi, G. A. Blake, Y-G. Han and C. Guo, 2018, “Fiber-array illumination: realizing high temporal multiplexing in multifocal multiphoton microscopy with simplicity”, Scientific Reports, 8(1),14863. (SCI) (IF: 4.259; SCI ranking: 15.6%)

  • [3]     Yu, J. Y. Kim, J. Holland, D. B. Mou, Y. Chiu, H. Blake, G. A. Lee, W. Guo, C. L., 2018, “Multiphoton structured thin-plane imaging with a single optical path”, OPTICS LETTERS, 43(21),5271-5274. (SCI, SSCI, EI) (IF: 3.416; SCI ranking: 16.3%)

  • [4]     G-Y. Zhuo, M-Y. Chen, C-Y. Yeh, J-Y. Yu, C Guo, and F-J. Kao., 2017, “Fast determination of three­dimensional fibril orientation of type­I collagen via macroscopic chirality”, APPLIED PHYSICS LETTERS, 110, 023702. (SCI) (IF: 3.411; SCI ranking: 19.6%)

  • [5]     T-Y. Chang, C. Chen, Y-C. Chang, C-H. Lu, M. Lee, S-T. Lu, D-Y. Wang, A. Wang, C. Guo and P-L. Cheng, 2017, “Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery”, ELIFE. (SCI) (IF: 7.725; SCI ranking: 4.7%)

  • [6]     Muller, N. Piel, M. Calvez, V. Voituriez, R. Goncalves-Sa, J. Guo, C. L. Jiang, X. Murray, A. Meunier, N, 2016, “A Predictive Model for Yeast Cell Polarization in Pheromone Gradients”, PLoS Computational Biology, 12(4), e1004795. (SCI) (IF: 4.542; SCI ranking: 14.1%,7%)

  • [7]     Meng-Tsung Hsu, Chin-Lin Guo, Angela Y. Liou, Ting-Ya Chang, Ming-Chong Ng, Yen-Lin Wu, Bogdab I. Florea, Herman S. Overkleeft, Yen-Ling Wu, Jung-Chi Liao, and Pei-Lin Cheng , 2015, “Stage-Dependent Axon transport of Proteasomes Contributes to Axon Development ”, Developmental Cell, in press. (SCI) (IF: 9.616; SCI ranking: 8.9%,2.4%)

  • [8]     Mou Y, Yu JY, Wannier TM, Guo CL, Mayo SL, 2015, “Computational design of co-assembling protein-DNA nanowires.”, Nature, 525(7568), 230-3. (SCI) (IF: 41.577; SCI ranking: 1.6%)

  • [9]     Guo CL, Cheng PL, 2015, “Second messenger signaling for neuronal polarization: cell mechanics-dependent pattern formation.”, Developmental neurobiology, 75(4), 388-401. (SCI) (IF: 2.598; SCI ranking: 38.1%,60.9%)

  • [10]     Abrams MJ, Basinger T, Yuan W, Guo CL, Goentoro L, 2015, “Self-repairing symmetry in jellyfish through mechanically driven reorganization.”, Proceedings of the National Academy of Sciences of the United States of America, 112(26), E3365-73. (SCI) (IF: 9.504; SCI ranking: 7.8%)

  • [11]     Guo CL, 2013, “Mechanical models for the self-organization of tubular patterns.”, Biomatter, 3(3).

  • [12]     Guo CL, Harris NC, Wijeratne SS, Frey EW, Kiang CH, 2013, “Multiscale mechanobiology: mechanics at the molecular, cellular, and tissue levels.”, Cell & bioscience, 3(1), 25. (SCI) (IF: 3.405; SCI ranking: 37.5%)

  • [13]     J-Y. Yu, D. B. Holland, G. A. Blake, and C. Guo, 2013, “The wide Field optical sectioning of a microlens array and structural illumination-based plane-projection multi-photon microscopy”, OPTICS EXPRESS, 21, 2097-109. (SCI) (IF: 3.356; SCI ranking: 20.2%)

  • [14]     Guo CL, Ouyang M, Yu JY, Maslov J, Price A, Shen CY, 2012, “Long-range mechanical force enables self-assembly of epithelial tubular patterns.”, Proceedings of the National Academy of Sciences of the United States of America, 109(15), 5576-82. (SCI) (IF: 9.504; SCI ranking: 7.8%)

  • [15]     A. Grosberg, P-L. Kuo, C. Guo, N. A. Geisse, M-A. Bray, W. J. Adams, S. P. Sheehy, and K. K. Parker, 2011, “Self-organization of muscle cell structure and function”, PLoS Computational Biology, 7:e1001088. (SCI) (IF: 3.955; SCI ranking: 16.5%,8.5%)

  • [16]     J-Y. Yu, C-H. Kuo, D. B. Holland, Y-Y. Chen, M. Ouyang, G. A. Blake, R. Zadoyan, and C. Guo, 2011, “Wide-field optical sectioning for live-tissue imaging by plane-projection multi-photon microscopy”, JOURNAL OF BIOMEDICAL OPTICS, 16, 116009. (SCI) (IF: 2.367; SCI ranking: 49.4%,36.2%,41.1%)

  • [17]     Z. Chang, C. Guo, I. Ahronowitz, A. O. Stemmer-Rachamimov, M. MacCollin, F. P. Nunes, 2009, “A role for the p53 pathway in the pathology of meningiomas with NF2 loss. Journal of Neuro-oncology”, JOURNAL OF NEURO-ONCOLOGY, 9, 265-270. (SCI) (IF: 3.06; SCI ranking: 54.3%,39.6%)

  • [18]     P-W. Fok, C. Guo, and T. Chou, 2008, “Guanine-mediated adsorption of DNA repair proteins”, JOURNAL OF CHEMICAL PHYSICS, 129, 235101. (SCI) (IF: 2.843; SCI ranking: 46.3%,35.1%)

  • [19]     Mechanisms underlying sequence independent beta-sheet formation, 2002, “C. Guo, M. Cheung, D.A. Kessler, and H Levine”, JOURNAL OF CHEMICAL PHYSICS, 116, 4353-4365. (SCI) (IF: 2.843; SCI ranking: 46.3%,35.1%)

  • [20]     C. Guo and H. Levine, 2000, “A statistical mechanics model for TNFR1 signaling”, JOURNAL OF BIOLOGICAL PHYSICS, 26, 219-234. (SCI) (IF: 1; SCI ranking: 87.5%)

  • [21]     C. Guo, H. Levine and D.A. Kessler, 2000, “How does a beta-hairpin fold? Competition between topology and heterogeneity in a solvable model”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97, 10775-10779. (SCI) (IF: 9.504; SCI ranking: 7.8%)

  • [22]     C. Guo, H. Levine and D.A. Kessler, 2000, “Two state behavior in a solvable model of beta-hairpin folding. Physical Review Letters”, PHYSICAL REVIEW LETTERS, 84, 3490-3493. (SCI) (IF: 8.839; SCI ranking: 7.7%)

  • [23]     C.H. Lee, C. Guo, and J. Wang, 1998, “Optical measurement of the viscoelastic and biochemical responses of living cells to mechanical perturbation”, OPTICS LETTERS, 23, 307-309. (SCI) (IF: 3.589; SCI ranking: 14.9%)

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