專題演講 Seminar

Title

To fold or not to fold – that is the question

Speaker

温福來助理教授 (台北教育大學自然科學教育學系)

Assistant Professor Fu-Lai Wen (Department of Science Education, National Taipei University of Education, Taiwan)

Abstract

Tissues consist of many cellsthat work together to perform a specific function for the organism.
Each cell within a tissue constantly exhibits rich dynamics, such as cell shape changes and cell
movement, which generates the mechanical forces necessary for tissue shape formation during
embryo development and tissue repair in wound healing process. Understanding of how
individual cell dynamics orchestrate the global tissue behavior is thus central to the fields of
biology and biomedical engineering, and presents a new frontier in the statistical physics of
active matter. In this seminar, I will discuss how physics can be useful in addressing the
complex problems found in nonequilibrium living systems. Particularly, I will focus on how
tissues fold – the first step that shapes embryos into their functional morphologies. Using a
vertex-based mechanical model, I will show that expansion of a contractile ring within a tissue
can induce a buckling instability which leads to a fold formation reminiscent of those observed
during tracheal development in the Drosophila (fruit fly) embryo.

Language

演講語言 (Language): in English

Hosted by

梁鈞泰 兼任研究員
Leung, Kwan-Tai / Adjunct Research Fellow