• NIH Genomics Science Training Program, 2003-2005
• Postdoctoral Researcher, University of Wisconsin-Madison, 2003-2005

期刊論文

(1) Jia-Wei Yeh, Alessandro Taloni, Yeng-Long Chen, Chia-Fu Chou, 2012, “Single Molecule Tug- of- War of DNA at Micro-Nanofluidic Interfaces”, NANO LETTERS, 12, 1597. (SCI) (IF: 13.198; SCI ranking: 5.2%,3%,6.1%,3%,4%,5.8%) (2) Po-keng Lin, Chih-Chen Hsieh, Yeng-Long Chen*, Chia-Fu Chou*, 2012, “ The Effects of Topology and Ionic Strength on Double-Stranded DNA Confined in Nanoslits”, MACROMOLECULES, 45 , 2920. (SCI) (IF: 5.167; SCI ranking: 6.3%) (3) I. Stachiv, A. I. Fedorchenko, and Y.-L. Chen*, 2012, “Mass detection by means of the vibrating nanomechanical resonators”, APPLIED PHYSICS LETTERS, 100, 093110. (SCI) (IF: 3.844; SCI ranking: 13.6%) (4) Govind A. Hegde, Jen-fang Chang, Yeng-long Chen*, and Rajesh Khare*, 2011, “Structural and Dynamic Properties of Ring Polymers in Solution: A Comparison between Molecular Dynamics, Multiple Particle Collision Dynamics and Lattice Boltzmann Simulations”, J CHEM PHYS, 135,184901. (SCI) (IF: 3.333; SCI ranking: 21.2%) (5) P.-K. Lin, J.-F. Chang, Y.-L. Chen* , 2011, “Partial hydrodynamic screening of confined linear and circular ds-DNA dynamics”, PHYSICAL REVIEW E, 84,031917. (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (6) A. Hammack, Y.-L. Chen, J. Kreft* , 2011, “Role of dissolved salts in thermophoresis of DNA: Lattice Boltzmann based simulations”, PHYSICAL REVIEW E, 83,031915. (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (7) Y.-L. Chen*, P.-K. Lin, and C.F. Chou , 2010, “Generalized force-extension relation for worm-like chains in slit confinement”, Macromolecules, ma102268b. (SCI) (IF: 5.167; SCI ranking: 6.3%) (8) C.-W. Hsu and Y.-L. Chen*, 2010, “Migration and fractionation of deformable particles in microchannel”, J. Chem. Phys, 133, 034906. (SCI) (IF: 3.333; SCI ranking: 21.2%) (9) S. Ramakrishnan*, S. A. Shah, L. Ruggeri, Y. L. Chen, K. S. Schweizer, and C. F. Zukoski , 2009, “Collective Diffusion in Colloid-Polymer Suspensions: Relative Role of Thermodynamics and Hydrodynamics”, Langmuir, 25, 10507. (SCI) (IF: 4.186; SCI ranking: 18.8%,20.9%,12.9%) (10) Kyubong Jo, Yeng-Long Chen, Juan J. de Pablo and David C. Schwartz, 2009, “Elongation and migration of single DNA molecules in microchannels using oscillatory shear flows”, LAB ON A CHIP, 9, 2348. (SCI) (IF: 5.67; SCI ranking: 8.3%,14.3%,19.7%) (11) Po-Keng Lin, Keng-hui Lin,Chi-Cheng Fu, K.-C. Lee,Pei-Kuen Wei, Woei-Wu Pai, Pei-Hsi Tsao, Y.-L. Chen* and W. S. Fann*, 2009, “One-Dimensional Dynamics and Transport of DNA Molecules in a Quasi-Two-Dimensional Nanoslit”, Macromolecules, 42, 1770. (SCI) (IF: 5.167; SCI ranking: 6.3%) (12) J.K. Kreft, Y.-L. Chen*, and H.-C. Chang, 2008, “Conformation and trapping rate of DNA at a convergent stagnation point”, Phys. Rev. E, 77, 030801(R). (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (13) R. Wang, Y.-L. Chen, J. Hu, and G. Xue , 2008, “Depletion-induced surface alignment of asymmetric diblock copolymer in selective solvents”, J. Chem. Phys., 129, 044907. (SCI) (IF: 3.333; SCI ranking: 21.2%) (14) Y.-L. Chen*, H. Ma, M.D. Graham, J.J. de Pablo, 2007, “Modeling DNA in confinement: A comparison between Brownian dynamics and lattice Boltzmann method”, Macromolecules, 40, 5978. (SCI) (IF: 5.167; SCI ranking: 6.3%) (15) J.K. Kreft and Y.-L. Chen, 2007, “Simulations of DNA thermal diffusion in a microchannel”, Phys. Rev. E, 76,021912. (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (16) P.-K. Lin, C.-C. Fu., Y.-L. Chen, Y.-R. Chen, P.-K. Wei, C.H. Kuan and W.S. Fann, 2007, “Static Conformation and Dynamics of Single DNA Molecules Confined in Nanoslits”, Phys. Rev. E, 76, 011806. (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (17) R. Wang, Z. Jiang, G. Xue and Chen, Yeng-Long, 2006, “ Surface-induced phase transition of asymmetric diblock copolymer in selective solvents”, J. Phys. Chem. B, 110, 22726. (SCI) (IF: 3.696; SCI ranking: 23.9%) (18) Y.-L. Chen, V. Kobelev, K.S. Schweizer, 2005, “Barrier Hopping, Viscous Flow, and Kinetic Gelation in Nanoparticle-Polymer Suspensions”, Phys. Rev. E, 71, 041405. (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (19) Y.-L. Chen, K. Jo, D.C. Schwartz, M.D. Graham, J.J. de Pablo , 2005, “DNA Molecules in Microfluidic Oscillatory Flow”, Macromolecules, 38, 6608. (SCI) (IF: 5.167; SCI ranking: 6.3%) (20) M. Doxastakis, Y.-L. Chen , J.J. de Pablo , 2005, “Potential of mean force between two small colloids in a solution of nonadsorbing polymers”, J. Chem. Phys., 123, 034901. (SCI) (IF: 3.333; SCI ranking: 21.2%) (21) Y.-L. Chen, M.D. Graham, J.J. de Pablo, G.C. Randall, M. Gupta, and P.S. Doyle , 2004, “Conformation and Dynamics of Single DNA in Parallel-Plate Slit Microchannels”, Phys. Rev. E, 70, 060901(R). (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (22) S. Ramakrishnan, Y.-L. Chen, K.S. Schweizer*, and C.F. Zukoski* , 2004, “Gel Structure and Elastic Properties of Polymer-Colloid Mixtures”, Phys. Rev. E, 70, 040401(R). (SCI) (IF: 2.255; SCI ranking: 32.3%,10.9%) (23) Y.-L. Chen, K.S. Schweizer*, 2004, “Liquid State Theory of Structure, Thermodynamics, and Phase Separation in Suspensions of Rod Polymers and Hard Spheres”, JOURNAL OF PHYSICAL CHEMISTRY B, 108, 6687. (SCI) (IF: 3.696; SCI ranking: 23.9%) (24) Y.-L. Chen, K.S. Schweizer*, 2004, “Microscopic Theory of Gelation and Elasticity in Polymer-Particle Suspensions”, J. Chem. Phys., 120, 7212. (SCI) (IF: 3.333; SCI ranking: 21.2%) (25) M. Doxastakis, Y.-L. Chen, O. Guzmán, and J.J. de Pablo*, 2004, “Polymer-Particle Mixtures: Depletion and Packing Effects”, J. Chem. Phys, 120, 9335. (SCI) (IF: 3.333; SCI ranking: 21.2%) (26) S.A. Shah, Y.-L. Chen, S. Ramakrishnan, K.S. Schweizer*, and C.F. Zukoski* , 2003, “Microstructure of Dense Colloid-Polymer Suspensions and Gels”, JOURNAL OF PHYSICS-CONDENSED MATTER, 15, 4751. (SCI) (IF: 2.546; SCI ranking: 26.1%) (27) S.A. Shah, Y.-L. Chen, C. F. Zukoski*, and K.S. Schweizer* , 2003, “Phase Behavior and Concentration Fluctuations in Suspensions of Hard Spheres and Near Ideal Polymers”, J. Chem. Phys., 118, 3350. (SCI) (IF: 3.333; SCI ranking: 21.2%) (28) Y.-L. Chen, M. Fuchs, and K.S. Schweizer* , 2003, “Phase Separation in Colloid-Polymer Suspensions: Role of Solvent Quality, Physical Mesh, and Nonlocal Entropic Repulsion”, J. Chem. Phys., 118, 3880. (SCI) (IF: 3.333; SCI ranking: 21.2%) (29) 4. S.A. Shah, S. Ramakrishnan, Y.-L. Chen, K.S. Schweizer*, and C.F. Zukoski* , 2003, “Scattering Studies of the Structure of Colloid-Polymer Suspensions and Gels”, Langmuir, 19, 5128. (SCI) (IF: 4.186; SCI ranking: 18.8%,20.9%,12.9%) (30) S.A. Shah, Y.-L. Chen, K.S. Schweizer*, and C.F. Zukoski*, 2003, “Viscoelasticity and Rheology of Depletion Flocculated Gels and Fluids”, J. Chem. Phys., 119, 8747. (SCI) (IF: 3.333; SCI ranking: 21.2%) (31) Y.-L. Chen and K.S. Schweizer* , 2002, “Collective Structure and Dynamics in Dense Colloid-Rod Polymer Suspension”, LANGMUIR, 18, 7354. (SCI) (IF: 4.186; SCI ranking: 18.8%,20.9%,12.9%) (32) Y.-L. Chen, K.S. Schweizer*, 2002, “Depletion Interaction In Suspensions of Spheres And Rod Polymers”, J CHEM PHYS, 117, 1351. (SCI) (IF: 3.333; SCI ranking: 21.2%)

學術會議(研討會)論文

專書
專書著作 主編之專書

專書內之論文

技術報告

其他論文

(1)	國內學術研究獎項	2011, 2012, 2013, 2014, 2015	AS Career Development Award
(2)	其他國際學術研究獎項	2007-10	C.N. Yang Visiting Scholar, CUHK
(3)	其他國際學術研究獎項	2006-08	2006年美國李氏傳統基金會獎(Li Foundation Heritage Prize)

(1)

西元年：2012 研究人員(中)：陳彥龍、葉佳唯、Alessandro Taloni、周家復 研究人員(英)：CHEN, YENG-LONG, Jia-Wei Yeh, Alessandro Taloni, Chia-Fu Chou 研究成果名稱(中)：奈米流道引致之單分子DNA拔河 研究成果名稱(英)：Entropic tug-of-war with DNA in a nanofluidic device 簡要記述(中)：單分子DNA穿隧奈米尺寸大小的流道，需克服因自由度減少而造成的熵能屏障，此行為在生物現象中扮演重要的角色。例如病毒傳送核酸DNA到宿主細胞。我們和周家復研究員的研究團隊利用微奈米製程與封裝技術，並結合高解析螢光顯微術為基礎，利用電控的方式操作單分子DNA使其跨越微奈米流道介面所形成的熵屏障，形成特殊且有趣的單一DNA左臂對右臂的拔河現象。參考我們先前發展DNA在納米流道的(力-擴展)關係，我們計算了熵驅動的拔河力量，以及力和通道高度的關係。 簡要記述(英)：Double stranded DNA molecules have a persistence length of approximately 50nm. Confining DNA molecules in nanochannels smaller than 100 nm strongly affects their physical properties and restricts DNA configuration entropy. Using the large difference of DNA entropy in nano- and micro-channels, we and our collaborators constructed a nanofluidic device with two micro-to-nano interfaces. The parts of a DNA molecule in the microchannel would "exert" effect forces that pulls on the DNA from both micro-nano interfaces, leading to a tug-of-war. Using the force-extension relation we previously developed (Chen et al, Macromolecules 2010), we determined the tug-of-war forces and how it depends on the channel height. This study provides new insight into the entropy-driven DNA motion for DNA translocation and DNA transcription inside the cell. 主要相關著作： Jia-Wei Yeh, Alessandro Taloni, Yeng-Long Chen, Chia-Fu Chou, 2012, “Single Molecule Tug- of- War of DNA at Micro-Nanofluidic Interfaces”, NANO LETTERS, 12, 1597. (SCI) (IF: 13.198; SCI ranking: 5.2%,3%,6.1%,3%,4%,5.8%)

(2)

西元年：2010 研究人員(中)：陳彥龍、許家瑋 研究人員(英)：CHEN, YENG-LONG, Chia-Wei Hsu 研究成果名稱(中)：軟粒子於微流管內之流体力學 研究成果名稱(英)：Migration of soft deformable particles in microflow 簡要記述(英)：We used a hybrid particle dynamics - fluid dynamics simulation method to determine the migration of soft particles in micro-capillary. It is discovered that the particle deformation couples with the flow dynamic to "push" the particles to the center fast stream. This explains the non-Newtonian rheology of soft particle suspensions. 主要相關著作： C.-W. Hsu and Y.-L. Chen*, 2010, “Migration and fractionation of deformable particles in microchannel”, J. Chem. Phys, 133, 034906. (SCI) (IF: 3.333; SCI ranking: 21.2%)